Intron Recognition Comes of AGe

Nat Struct Biol. 2000 Jan;7(1):14-6. doi: 10.1038/71207.

Abstract

The molecular basis for the consensus sequence at the 3' ends of introns in higher eukaryotes has now been elucidated. However, this discovery does not explain all aspects of 3' splice site selection.

Publication types

  • News

MeSH terms

  • Animals
  • Base Sequence
  • Consensus Sequence / genetics*
  • Conserved Sequence / genetics
  • Evolution, Molecular
  • Exons / genetics
  • Humans
  • Introns / genetics*
  • Nuclear Proteins*
  • RNA / genetics
  • RNA / metabolism
  • RNA Splicing / genetics*
  • Regulatory Sequences, Nucleic Acid / genetics*
  • Ribonucleoproteins / metabolism
  • Spliceosomes / metabolism
  • Splicing Factor U2AF

Substances

  • Nuclear Proteins
  • Ribonucleoproteins
  • Splicing Factor U2AF
  • U2AF2 protein, human
  • RNA