Disorders of hyperpigmentation

Dermatol Clin. 2000 Jan;18(1):91-8, ix. doi: 10.1016/s0733-8635(05)70150-9.


Hyperpigmentation is a common disorder of the skin, particularly in brown-skinned patients. Melasma is a common cause of facial hyperpigmentation and can be resistant to treatment. A combination of topical creams and gels, chemical peels, and sunscreens may be necessary for significant improvement. Erythema dyschromicum perstans is a dermal pigmentation seen on the trunk and proximal extremities, most commonly presenting in dark-skinned Hispanics. Drug-induced and postinflammatory hyperpigmentation may last for many months after the offending drug or dermatitis has been eliminated. These disorders, including their management, is reviewed in this article.

Publication types

  • Review

MeSH terms

  • Erythema / therapy
  • Female
  • Humans
  • Hyperpigmentation* / therapy
  • Melanosis / therapy