Lens development

Eye (Lond). 1999 Jun:13 ( Pt 3b):425-37. doi: 10.1038/eye.1999.117.


This review gives a brief account of the main processes of lens development, including induction, morphogenesis, differentiation and growth. It describes what is known about the molecules and mechanisms that control and regulate these processes. Some of the recent progress made in understanding the molecular basis of lens development is highlighted along with some of the challenging areas for future research.

Publication types

  • Review

MeSH terms

  • Animals
  • Cataract / metabolism
  • Cell Differentiation
  • Cell Movement
  • Chick Embryo
  • Crystallins / metabolism
  • Embryonic Induction
  • Fibroblast Growth Factors / physiology
  • Humans
  • Lens, Crystalline / embryology*
  • Mice
  • Morphogenesis
  • Rats


  • Crystallins
  • Fibroblast Growth Factors