IL-13 in allergy: home at last

Curr Opin Immunol. 1999 Dec;11(6):610-4. doi: 10.1016/s0952-7915(99)00025-4.


The immune response to allergic challenge is thought to include important effects mediated by cytokines. Of considerable interest to immunologists and parasitologists is the distinction between two closely related cytokines, IL-4 and IL-13. Although overlapping functions are inevitable, studies over the past year reveal a distinct role for IL-13 in mediating the physiologic response to a diverse array of allergens and parasites.

Publication types

  • Review

MeSH terms

  • Animals
  • Asthma / immunology
  • B-Lymphocytes / immunology
  • Helminthiasis / immunology
  • Humans
  • Hypersensitivity / immunology*
  • Interleukin-13 / immunology*
  • Intestinal Diseases, Parasitic / immunology
  • T-Lymphocytes / immunology


  • Interleukin-13