Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2000 Jan 14;287(5451):303-5.
doi: 10.1126/science.287.5451.303.

Engineering the Provitamin A (Beta-Carotene) Biosynthetic Pathway Into (Carotenoid-Free) Rice Endosperm

Affiliations
Free article

Engineering the Provitamin A (Beta-Carotene) Biosynthetic Pathway Into (Carotenoid-Free) Rice Endosperm

X Ye et al. Science. .
Free article

Abstract

Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.

Comment in

Similar articles

See all similar articles

Cited by 303 articles

See all "Cited by" articles

Publication types

MeSH terms

LinkOut - more resources

Feedback