The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation

Phytother Res. 2000 Feb;14(1):43-4. doi: 10.1002/(sici)1099-1573(200002)14:1<43::aid-ptr522>;2-h.


Dandelions have long been used in herbal medicine for their choleretic, diuretic, antiinflammatory, appetite-stimulating and laxative properties. An antioxidant property can be supposed as a basis of their-therapeutic effects. To understand the mechanism of the drug's action, the effects of natural extracts on a microsomal fraction of rat liver were examined. The extracts diminished the enzymatically induced-lipid peroxidation and reduced the cytochrome c with and without NADPH in a concentration dependent manner.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antioxidants / pharmacology*
  • Lipid Peroxidation / drug effects*
  • Microsomes, Liver / drug effects*
  • Microsomes, Liver / metabolism
  • Plant Extracts / pharmacology*
  • Plants, Medicinal / chemistry*
  • Rats


  • Antioxidants
  • Plant Extracts