Abstract
An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana led to the isolation of two novel antibacterial and antifungal flavanones together with a known flavanone. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-[2-butenyl])-(2S)-flavanone, 4',5,7-trihydroxy-6-methyl-8-(3-methyl-[2-butenyl])-(2S)-flavanone and 4',5-dihydroxy-7-methoxy-6-(3-methyl-[2-butenyl])-(2S)-flavanone on the basis of their UV, 1D and 2D-NMR spectra.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents
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Anti-Infective Agents / chemistry*
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Anti-Infective Agents / isolation & purification
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Anti-Infective Agents / pharmacology
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Antifungal Agents / chemistry*
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Antifungal Agents / isolation & purification
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Antifungal Agents / pharmacology
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Candida albicans / drug effects
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Candida albicans / growth & development
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Flavonoids / chemistry*
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Flavonoids / isolation & purification
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Flavonoids / pharmacology
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Plant Extracts / analysis*
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Plants / chemistry*
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Spectrometry, Mass, Secondary Ion
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Staphylococcus aureus / drug effects
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Staphylococcus aureus / growth & development
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents
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Antifungal Agents
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Flavonoids
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Plant Extracts