Maximal oxygen uptake "classical" versus "contemporary" viewpoints

Med Sci Sports Exerc. 2000 Jan;32(1):85-8. doi: 10.1097/00005768-200001000-00013.


In two articles Timothy Noakes proposes a new physiological model in which skeletal muscle recruitment is regulated by a central "govenor," specifically to prevent the development of a progressive myocardial ischemia that would precede the development of skeletal muscle anaerobiosis during maximal exercise. In this rebuttal to the Noakes' papers, we argue that Noakes has ignored data supporting the existing hypothesis that under normal conditions cardiac output is limiting maximal aerobic power during dynamic exercise engaging large muscle groups.

Publication types

  • Comment

MeSH terms

  • Anaerobic Threshold / physiology
  • Blood Pressure / physiology
  • Cardiac Output / physiology
  • Exercise / physiology
  • Heart / physiology
  • Humans
  • Muscle Contraction / physiology
  • Muscle, Skeletal / anatomy & histology
  • Muscle, Skeletal / metabolism*
  • Myocardial Ischemia / metabolism
  • Myocardial Ischemia / prevention & control
  • Oxygen / blood
  • Oxygen Consumption / physiology*
  • Physical Endurance / physiology
  • Stroke Volume / physiology


  • Oxygen