DNA replication and cancer

Crit Rev Oncog. 1999;10(4):275-91.

Abstract

Current knowledge of the mechanisms of DNA replication and their implications in oncogenesis is reviewed. Progress in this area will continue to provide new tools in the clinical characterization and treatment of a variety of neoplasms.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Cycle
  • Chromosome Fragility
  • DNA Repair
  • DNA Replication*
  • Humans
  • Microsatellite Repeats
  • Mutation
  • Neoplasms / genetics*
  • Signal Transduction
  • Telomerase / metabolism

Substances

  • Telomerase