Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2000 Feb;22(2):124-37.
doi: 10.1002/(SICI)1521-1878(200002)22:2<124::AID-BIES4>3.0.CO;2-E.

Mammalian Chromodomain Proteins: Their Role in Genome Organisation and Expression

Affiliations
Review

Mammalian Chromodomain Proteins: Their Role in Genome Organisation and Expression

D O Jones et al. Bioessays. .

Abstract

The chromodomain is a highly conserved sequence motif that has been identified in a variety of animal and plant species. In mammals, chromodomain proteins appear to be either structural components of large macromolecular chromatin complexes or proteins involved in remodelling chromatin structure. Recent work has suggested that apart from a role in regulating gene activity, chromodomain proteins may also play roles in genome organisation. This article reviews progress made in characterising mammalian chromodomain proteins and emphasises their emerging role in the regulation of gene expression and genome organisation. BioEssays 22:124-137, 2000.

Similar articles

See all similar articles

Cited by 85 articles

See all "Cited by" articles

Substances

LinkOut - more resources

Feedback