Radiation therapy in the treatment of leukemic infiltrates of the testes

Radiology. 1976 Sep;120(3):681-2. doi: 10.1148/120.3.681.

Abstract

Testicular infiltration developed in 6 of 56 boys with lymphoblastic leukemia. All exhibited platelet counts under 100,000, indicating poor prognosis. Patients were treated with vincristine, prednisone, and craniomemingeal prophylaxis (2,400 rads/12 fx) extending to the C2 level. Only 3 patients did not suffer recurrence of testicular disease during their multiple leukemic relapses. Alternate treatment courses are suggested.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acute Disease
  • Brain Neoplasms / radiotherapy
  • Child
  • Child, Preschool
  • Humans
  • Leukemia, Lymphoid / drug therapy
  • Leukemia, Lymphoid / radiotherapy*
  • Male
  • Prednisone / therapeutic use
  • Prognosis
  • Testicular Neoplasms / drug therapy
  • Testicular Neoplasms / radiotherapy*
  • Thrombocytopenia / complications
  • Vincristine / therapeutic use

Substances

  • Vincristine
  • Prednisone