Translational repression: a duet of Nanos and Pumilio

Curr Biol. 2000 Jan 27;10(2):R81-3. doi: 10.1016/s0960-9822(00)00283-9.

Abstract

Recent studies have shed new light on translational repression by Nanos and Pumilio proteins. The ancestral function of this repression mechanism appears to be in early germline development; later, species-specific applications in embryonic patterning and spermatogenesis-oogenesis switching evolved.

Publication types

  • Review

MeSH terms

  • Animals
  • Body Patterning / genetics
  • Drosophila Proteins*
  • Insect Proteins / genetics*
  • Male
  • Oogenesis / genetics
  • Protein Biosynthesis*
  • RNA-Binding Proteins*
  • Spermatogenesis / genetics

Substances

  • Drosophila Proteins
  • Insect Proteins
  • RNA-Binding Proteins
  • pum protein, Drosophila
  • nos protein, Drosophila