RING for destruction?

Curr Biol. 2000 Jan 27;10(2):R84-7. doi: 10.1016/s0960-9822(00)00287-6.


Ubiquitination targets proteins for degradation and is a potent regulator of cellular protein function. Recent results implicate the RING finger domain in specific ubiquitination events; it is possible that all RING proteins act as E3 ubiquitin protein ligases, with implications for a variety of biological areas.

Publication types

  • Review

MeSH terms

  • Amino Acid Motifs*
  • Amino Acid Sequence
  • Proteins / chemistry
  • Proteins / metabolism*
  • Ubiquitins / metabolism*


  • Proteins
  • Ubiquitins