Subacute combined degeneration of the spinal cord with involvement of the anterior columns: a new MRI finding

Neuroradiology. 2000 Feb;42(2):115-7. doi: 10.1007/s002340050027.


We present a case of vitamin B12 deficiency and subacute combined degeneration in a patient with a gastrectomy. MRI showed high-signal lesions on T2-weighted images in both the posterior and anterior columns, associated with minor thoracic spinal cord expansion. The patient was treated with B12 supplements and clinical improvement was associated with reduction of the size of the lesions on MRI.

Publication types

  • Case Reports

MeSH terms

  • Gastrectomy / adverse effects
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Neurodegenerative Diseases / diagnosis*
  • Neurodegenerative Diseases / etiology
  • Spinal Cord / pathology
  • Spinal Cord Diseases / diagnosis*
  • Spinal Cord Diseases / etiology
  • Vitamin B 12 / therapeutic use
  • Vitamin B 12 Deficiency / complications
  • Vitamin B 12 Deficiency / drug therapy


  • Vitamin B 12