Signal transduction in the plant immune response

Trends Biochem Sci. 2000 Feb;25(2):79-82. doi: 10.1016/s0968-0004(99)01532-7.


Complementary biochemical and genetic approaches are being used to dissect the signaling network that regulates the innate immune response in plants. Receptor-mediated recognition of invading pathogens triggers a signal amplification loop that is based on synergistic interactions between nitric oxide, reactive oxygen intermediates and salicylic acid. Alternative resistance mechanisms in Arabidopsis are deployed against different types of pathogens; these mechanisms are mediated by either salicylic acid or the growth regulators jasmonic acid and ethylene.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Nitric Oxide / metabolism
  • Oxygen / metabolism
  • Plants / genetics
  • Plants / immunology*
  • Plants / metabolism*
  • Reactive Oxygen Species
  • Salicylic Acid / metabolism
  • Signal Transduction*


  • Reactive Oxygen Species
  • Nitric Oxide
  • Salicylic Acid
  • Oxygen