Sirolimus-tacrolimus combination immunosuppression

Lancet. 2000 Jan 29;355(9201):376-7. doi: 10.1016/S0140-6736(99)03882-9.

Abstract

A series of 32 recipients of liver, kidney, or pancreas transplants who were treated with sirolimus and low-dose tacrolimus experienced a low rate of rejection and excellent graft function without drug-related toxic effects.

Publication types

  • Clinical Trial
  • Letter

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Drug Therapy, Combination
  • Female
  • Graft Rejection / prevention & control*
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Kidney Transplantation / immunology
  • Liver Transplantation / immunology
  • Male
  • Middle Aged
  • Pancreas Transplantation / immunology
  • Sirolimus / administration & dosage*
  • Tacrolimus / administration & dosage*

Substances

  • Immunosuppressive Agents
  • Sirolimus
  • Tacrolimus