D-dimer after delivery in uncomplicated pregnancies

Clin Exp Obstet Gynecol. 1999;26(3-4):211-2.


D-dimer is now widely used as a coagulation marker. During pregnancy the D-dimer level increases until term even in uncomplicated pregnancies. The aim of the study was to establish the D-dimer immediately after delivery in uncomplicated pregnancies. A rapid immunoturbidimetric assay for D-dimer determination was employed in 100 consecutive deliveries. D-dimer level increased significantly in all women after delivery (increase from 1 to more than 10 times over the normal range).

Conclusion: An increase in fibrinolysis is associated with pregnancy and delivery, and D-dimer level must be interpreted only in association with other clinical, laboratory and instrumental methods when pathological conditions (e.g. pulmonary embolism, deep vein thrombosis or disseminated coagulation) are suspected.

MeSH terms

  • Cesarean Section
  • Delivery, Obstetric
  • Female
  • Fibrin Fibrinogen Degradation Products / analysis*
  • Humans
  • Postpartum Period / physiology*
  • Pregnancy
  • Reference Values


  • Fibrin Fibrinogen Degradation Products