Abstract
A 60 year old woman with disseminated ductal carcinoma of the breast developed non-islet cell tumour induced hypoglycaemia (NICTH). The concentrations of the two insulin-like growth factors, IGF-I and IGF-II, were < 2 nmol/l and 94.1 nmol/l, respectively. The IGF-II to IGF-I ratio was > 47 (normal < 10). Insulin (< 3 mu/l) and C peptide (< 100 pmol/l) were both undetectable.
MeSH terms
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Adenocarcinoma, Papillary / blood*
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Adenocarcinoma, Papillary / pathology
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Bone Neoplasms / blood
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Bone Neoplasms / pathology
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Bone Neoplasms / secondary
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Breast Neoplasms / blood*
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Breast Neoplasms / pathology
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Female
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Humans
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Hypoglycemia / blood*
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Hypoglycemia / pathology
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Immunohistochemistry
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Insulin-Like Growth Factor I / analysis
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Insulin-Like Growth Factor II / analysis*
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Middle Aged
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Skin Neoplasms / blood
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Skin Neoplasms / pathology
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Skin Neoplasms / secondary
Substances
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Insulin-Like Growth Factor I
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Insulin-Like Growth Factor II