Huperzine-A Capsules Enhance Memory and Learning Performance in 34 Pairs of Matched Adolescent Students

Zhongguo Yao Li Xue Bao. 1999 Jul;20(7):601-3.

Abstract

Aim: To study the efficacy of huperzine-A capsules (Hup) on memory and learning performance of adolescent students.

Methods: Using double-blind and matched pair method, 34 pairs of junior middle school students complaining of memory inadequacy were divided into two groups by normal psychological health inventory (PHI), similar memory quotient (MQ), same sex and class. The Hup group was administrated orally 2 capsules of Hup (each contains Hup 50 micrograms) b.i.d., and the placebo group was given 2 capsules of placebo (starch and lactose inside) b.i.d. for 4 wk.

Results: At the end of trial, the Hup group's MQ (115 +/- 6) was more than that of the placebo group (104 +/- 9, P < 0.01), and the scores of Chinese language lesson in the Hup group were elevated markedly too.

Conclusion: The Hup capsules enhance the memory and learning performance of adolescent students.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Alkaloids
  • Capsules
  • Cholinesterase Inhibitors / pharmacology*
  • Double-Blind Method
  • Female
  • Humans
  • Learning / drug effects*
  • Male
  • Matched-Pair Analysis
  • Memory / drug effects*
  • Sesquiterpenes / pharmacology*
  • Wechsler Scales

Substances

  • Alkaloids
  • Capsules
  • Cholinesterase Inhibitors
  • Sesquiterpenes
  • huperzine A