Asymptomatic penile HPV infection: a prospective study

Int J STD AIDS. 2000 Feb;11(2):80-4. doi: 10.1177/095646240001100203.


The occurrence of human papillomavirus (HPV) among males was analysed with the polymerase chain reaction (PCR) method. Penile brush samples were taken once from 147 males attending for a control or for HPV non-related reasons, and consecutive samples were collected from 88 males re-attending the clinic. Of the males attending once, 13% (19/147) were HPV DNA positive and among the re-attenders 14% (12/88) were initially positive as compared with 33% (29/88) who were positive at least at one visit. Totally, 22 different HPV types were detected of which HPV 16 was most common, found in 6.4% (15/235), followed by HPV 42 found in 3.8% (9/235). Among 14 HPV-positive males with at least one follow-up, 7 had persistent infections with at least one HPV type, and transient HPV types were observed in 9; but in 5 of them new types appeared at follow-up. Among sexually-active males subclinical/latent HPV infection is common and repeated sampling increases its prevalence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • DNA, Viral / analysis
  • Humans
  • Male
  • Middle Aged
  • Papillomaviridae / classification*
  • Papillomavirus Infections / virology*
  • Penile Diseases / virology*
  • Polymerase Chain Reaction
  • Prospective Studies
  • Tumor Virus Infections / virology*


  • DNA, Viral