Parallel actin bundles and their multiple actin-bundling proteins

Curr Opin Cell Biol. 2000 Feb;12(1):72-8. doi: 10.1016/s0955-0674(99)00059-9.


Parallel actin bundles are present in a diverse array of structures, where they are critical determinants of cellular shape and physiology. In the past 18 months, new findings have solidified the concept that parallel actin bundles are assembled in cells through the sequential action of multiple actin-bundling proteins and have begun to shed light on the roles played by the individual actin-bundling proteins.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Actins / metabolism*
  • Animals
  • Cilia / metabolism
  • Cytoplasm / metabolism
  • Drosophila melanogaster / cytology
  • Drosophila melanogaster / metabolism
  • Hair Cells, Auditory / cytology
  • Hair Cells, Auditory / metabolism
  • Humans
  • Male
  • Microfilament Proteins / metabolism*
  • Microvilli / metabolism
  • Sertoli Cells / cytology
  • Sertoli Cells / metabolism


  • Actins
  • Microfilament Proteins
  • actin filament bundling proteins