How centrioles work: lessons from green yeast

Curr Opin Cell Biol. 2000 Feb;12(1):119-25. doi: 10.1016/s0955-0674(99)00065-4.


Centrioles are the organizing centers around which centrosomes assemble. Despite a century of study, the molecular details of centriole function and assembly remain largely unknown. Recent work has exploited the unique advantages of unicellular algae to reveal proteins that play central roles in centriole biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Centrioles / chemistry
  • Centrioles / genetics
  • Centrioles / metabolism*
  • Chlamydomonas / cytology*
  • Chlamydomonas / genetics
  • Microtubules / genetics
  • Microtubules / metabolism
  • Spindle Apparatus / metabolism