One hundred-twenty aged patients with kidney deficiency syndrome of ischemic cardio-cerebral vascular diseases were treated with Epimedium compound granules. The results showed that after therapeutic period the total and marked effective rates were 96.7%, 39.5% respectively in treatment group. The rates of improvement were 70% in electrocardiogram of the patients with coronary heart diseases, and 75% in electro-encephalogram of the patients with cerebral arterosclerosis. The therapeutic effectiveness in treatment group was better than that in control group treated with Su-Guan-Bian. According to experimental observation, the therapeutic effectiveness was related to the facts that Epimedium compound granules lower blood lipid have anti-free radicals and adjust balance between prostacyctin I2 and thromboxane A2(TXA2/PGI2).