In this study, four anesthetic agents of different forms and contents, namely: EMLA 5% Cream (lidocaine 2.5 percent, prilocaine 2.5 percent), Vision-Gel (benzocaine 20 percent), Anesthetic Tabs (tetracaine hydrochloride 0.68 mg, cincocain hydrochloride 0.02 mg), Xylocaine 10% aerosol (lidocaine 10 percent) were evaluated in terms of effectiveness in decreasing the intra-oral injection pain. Six groups each consisting of 20 children were constituted from 120 children aged between 10-15 years. The responses of the patients to the pain were evaluated using a visual analogue scale. Consequently, of all the other anesthetic agents used in the present study, Vision Gel was observed to be the most effective.