Abstract
We present the second human Y-specific minisatellite, MSY2 (DYS440). It consists of three or four copies of a 99-110bp repeat unit and is located about 1kb upstream of the DBY gene. The most common allele contains four units, but a three-unit allele has arisen on at least four occasions; in chimpanzees and orangutans, MSY2 contains only two units. It is therefore evolving slowly and provides a particularly useful polymorphic marker for Chinese populations.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Alleles
-
Animals
-
Base Sequence
-
Cell Line
-
China
-
DNA / chemistry
-
DNA / genetics
-
DNA Probes
-
Female
-
Genetic Markers
-
Genetic Variation
-
Humans
-
Male
-
Minisatellite Repeats / genetics*
-
Molecular Sequence Data
-
Pan troglodytes / genetics
-
Polymorphism, Genetic
-
Pongo pygmaeus / genetics
-
Sequence Alignment
-
Sequence Analysis, DNA
-
Sequence Homology, Nucleic Acid
-
Y Chromosome / genetics*
Substances
-
DNA Probes
-
Genetic Markers
-
DNA
Associated data
-
GENBANK/AF207845
-
GENBANK/AF207846