Bilirubin and jaundice in the micropremie

Clin Perinatol. 2000 Mar;27(1):171-9, vii. doi: 10.1016/s0095-5108(05)70012-9.


Although it has been customary to treat neonatal jaundice at lower serum bilirubin levels in low-birth weight infants than in term infants, the threshold bilirubin levels and long-term benefits for early treatment of preterm infants have not been validated. This article summarizes and evaluates existing evidence and strategies for early treatment of bilirubin in micropremies and recommends a conservative but flexible approach to early monitoring and phototherapy for jaundice in extremely low-birth weight infants.

Publication types

  • Review

MeSH terms

  • Bilirubin / metabolism*
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases* / diagnosis
  • Infant, Premature, Diseases* / metabolism
  • Infant, Premature, Diseases* / therapy
  • Infant, Very Low Birth Weight / metabolism*
  • Jaundice, Neonatal* / diagnosis
  • Jaundice, Neonatal* / metabolism
  • Jaundice, Neonatal* / therapy
  • Phototherapy


  • Bilirubin