Abstract
A collection of Lyngbya majuscula from Palau contained the peptides dolastatin 3 (1), homodolastatin 3 (2), and kororamide (3), together with aplysiatoxin (4), debromoaplysiatoxin (5), and oscillatoxin A (6). The structures of the new peptides homodolastatin 3 (2) and kororamide (3) were determined by interpretation of spectroscopic data and chemical degradation.
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Amino Acids / analysis
-
Depsipeptides*
-
Gas Chromatography-Mass Spectrometry
-
HIV Integrase Inhibitors / chemistry
-
HIV Integrase Inhibitors / isolation & purification*
-
Magnetic Resonance Spectroscopy
-
Mass Spectrometry
-
Molecular Conformation
-
Palau
-
Peptides, Cyclic / chemistry
-
Peptides, Cyclic / isolation & purification*
-
Peptides, Cyclic / pharmacology
-
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
-
Spectrophotometry, Infrared
-
Spectrophotometry, Ultraviolet
Substances
-
Amino Acids
-
Depsipeptides
-
HIV Integrase Inhibitors
-
Peptides, Cyclic
-
dolastatin 3
-
homodolastatin 3
-
kororamide