Function of the Ubiquitin-Proteasome Pathway in Auxin Response

Trends Biochem Sci. 2000 Mar;25(3):133-8. doi: 10.1016/s0968-0004(00)01544-9.

Abstract

The plant hormone auxin regulates many aspects of growth and development. Despite the importance of this hormone, the molecular basis for auxin action has remained elusive. Recent advances using molecular genetics in Arabidopsis have begun to elucidate the mechanisms involved in auxin signaling. These results suggest that protein degradation by the ubiquitin pathway has a central role in auxin response.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / metabolism
  • Arabidopsis Proteins*
  • Cysteine Endopeptidases / metabolism*
  • Gene Expression Regulation, Plant*
  • Growth Substances*
  • Indoleacetic Acids / physiology*
  • Monomeric GTP-Binding Proteins / genetics
  • Monomeric GTP-Binding Proteins / metabolism
  • Multienzyme Complexes / metabolism*
  • Mutation
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Proteasome Endopeptidase Complex
  • Saccharomyces cerevisiae Proteins*
  • Ubiquitins / metabolism*
  • Vesicular Transport Proteins
  • alpha Karyopherins

Substances

  • AXR1 protein, Arabidopsis
  • Arabidopsis Proteins
  • Growth Substances
  • Indoleacetic Acids
  • Multienzyme Complexes
  • Nuclear Proteins
  • Plant Proteins
  • Saccharomyces cerevisiae Proteins
  • Ubiquitins
  • Vesicular Transport Proteins
  • alpha Karyopherins
  • Cysteine Endopeptidases
  • Proteasome Endopeptidase Complex
  • Monomeric GTP-Binding Proteins
  • SAR1 protein, S cerevisiae