Left-right development: the roles of nodal cilia

Curr Biol. 2000 Feb 24;10(4):R149-51. doi: 10.1016/s0960-9822(00)00328-6.

Abstract

Cilia on the ventral side of the mouse node have been implicated in initiating the left-right axis during embryonic development, but how cilia relate to other factors in the left-right pathway and the mechanism by which cilia convey patterning information remain uncertain.

Publication types

  • Review

MeSH terms

  • Animals
  • Axis, Cervical Vertebra / physiology
  • Body Patterning / physiology*
  • Kinesin / genetics
  • Kinesin / physiology
  • Mice
  • Mice, Mutant Strains

Substances

  • Kif3a protein, mouse
  • Kinesin