Epstein-Barr virus dacryoadenitis

Am J Ophthalmol. 2000 Mar;129(3):372-5. doi: 10.1016/s0002-9394(99)00351-7.

Abstract

Purpose: To describe the clinical features of lacrimal gland inflammation associated with Epstein-Barr virus infection.

Methods: The clinical records, laboratory data, and radiographs of patients who had inflammation of one or both lacrimal glands that had begun less than 4 weeks previously were reviewed.

Results: Sixteen patients with dacryoadenitis were encountered between 1980 and 1996, a cumulative frequency of approximately one case per 10,000 new ophthalmic outpatients. Six individuals had serologic or other evidence of recent Epstein-Barr virus infection and were distinguished by the presence of regional lymphadenopathy, no purulent discharge, and a duration of symptoms of 6 weeks.

Conclusion: Epstein-Barr virus is a probable cause of unilateral and bilateral dacryoadenitis in young adults.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antigens, Viral / immunology
  • Capsid / immunology
  • Capsid Proteins*
  • Cephalexin / therapeutic use
  • Child
  • Child, Preschool
  • Dacryocystitis / diagnosis
  • Dacryocystitis / drug therapy
  • Dacryocystitis / virology*
  • Eye Infections, Viral* / diagnosis
  • Eye Infections, Viral* / drug therapy
  • Eye Infections, Viral* / etiology
  • Female
  • Herpesviridae Infections / complications*
  • Herpesviridae Infections / diagnosis
  • Herpesviridae Infections / drug therapy
  • Herpesvirus 4, Human / immunology
  • Herpesvirus 4, Human / isolation & purification*
  • Humans
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Lacrimal Apparatus / diagnostic imaging
  • Lacrimal Apparatus / virology*
  • Male
  • Middle Aged
  • Prednisolone / therapeutic use
  • Tomography, X-Ray Computed
  • Tumor Virus Infections / complications*
  • Tumor Virus Infections / diagnosis
  • Tumor Virus Infections / drug therapy
  • Viral Proteins / immunology

Substances

  • Antigens, Viral
  • Capsid Proteins
  • EBNA-LP protein, Human herpesvirus 4
  • Epstein-Barr viral capsid antigen
  • Epstein-Barr virus early antigen
  • Immunoglobulin G
  • Immunoglobulin M
  • Viral Proteins
  • Prednisolone
  • Cephalexin