Inactivation of human type A and B influenza viruses by tea-seed saponins

Biosci Biotechnol Biochem. 2000 Jan;64(1):184-6. doi: 10.1271/bbb.64.184.

Abstract

The effects of a mixture of tea-seed saponins obtained from the seeds of Camellia sinensis var. sinesis on human influenza viruses types A and B were investigated. At the concentrations of 60, 80, and 100 micrograms/ml, respectively, the mixture inactivated viruses A/Memphis/1/71 (H3N2), B/Lee/40, and A/PR/8/34 (H1N1) almost completely. The mixture also inactivated type A virus A/PR/8/34 after inoculation at concentrations of 1-30 micrograms/ml dose-dependently.

MeSH terms

  • Animals
  • Cell Line
  • Dogs
  • Humans
  • Influenza A virus / drug effects*
  • Influenza B virus / drug effects*
  • Plant Extracts / pharmacology
  • Saponins / pharmacology*
  • Seeds / chemistry
  • Tea / chemistry*

Substances

  • Plant Extracts
  • Saponins
  • Tea