Abstract
In neurons, cytoskeletal proteins are transported from where they are made - the cell body - along the axons, but it has long been disputed whether they are transported as subunits or polymers. A new analysis of neurofilament movement may help to resolve the controversy.
MeSH terms
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Animals
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Axonal Transport / physiology*
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Biological Transport
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Cells, Cultured
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Cytoskeleton / metabolism*
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DNA, Complementary / administration & dosage
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Green Fluorescent Proteins
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Humans
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Luminescent Proteins / genetics
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Models, Biological
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Neurites / metabolism
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Neurofilament Proteins / genetics
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Neurofilament Proteins / metabolism*
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Neurons / cytology
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Neurons / metabolism
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Recombinant Fusion Proteins / genetics
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Recombinant Fusion Proteins / metabolism
Substances
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DNA, Complementary
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Luminescent Proteins
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Neurofilament Proteins
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Recombinant Fusion Proteins
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neurofilament protein M
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Green Fluorescent Proteins