A reliable method for the simultaneous identification of H pylori and gastric metaplasia in the duodenum

J Clin Pathol. 1999 Dec;52(12):914-6. doi: 10.1136/jcp.52.12.914.


While an association of Helicobacter pylori infection with duodenal mucosa gastric metaplasia has been described, the details and extent of the interaction are lacking. One of the limiting factors has been the lack of a staining technique that allows simultaneous visualisation of the bacteria and gastric metaplasia in the duodenum. This report describes a new stain that allows the simultaneous visualisation of duodenal gastric metaplasia and H pylori and compares the new stain with the component stains.

MeSH terms

  • Duodenum / pathology*
  • Helicobacter Infections / diagnosis*
  • Helicobacter pylori / isolation & purification*
  • Humans
  • Metaplasia / diagnosis
  • Sensitivity and Specificity
  • Staining and Labeling / methods