Minimal change glomerulonephritis associated with hydatid disease

Clin Nephrol. 2000 Feb;53(2):152-5.

Abstract

A 63-year-old man presented to our department with dyspnea and peripheral edema. A cystic mass in the right upper abdomen, consistent with echinococcal disease was discovered. Proteinuria was also present, and a nephrotic syndrome was diagnosed. The kidney biopsy revealed minimal change glomerulonephritis. Treatment with the antiechinococcal drug albendazole induced complete remission of the nephrotic syndrome, suggesting an etiopathogenic role for a hydatid antigen in the development of an immune-mediated glomerulonephritis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Albendazole / administration & dosage
  • Anticestodal Agents / administration & dosage
  • Biopsy
  • Echinococcosis, Hepatic / complications*
  • Echinococcosis, Hepatic / diagnosis
  • Echinococcosis, Hepatic / drug therapy
  • Humans
  • Immunologic Tests
  • Kidney / pathology
  • Liver / diagnostic imaging
  • Male
  • Middle Aged
  • Nephrosis, Lipoid / diagnosis
  • Nephrosis, Lipoid / drug therapy
  • Nephrosis, Lipoid / etiology*
  • Nephrotic Syndrome / diagnosis
  • Nephrotic Syndrome / drug therapy
  • Nephrotic Syndrome / etiology
  • Radionuclide Imaging
  • Ultrasonography

Substances

  • Anticestodal Agents
  • Albendazole