Abstract
Recent advances in gene array technology and isolation of lymphocytes now allow comprehensive analysis of gene expression in many different types of T cells. So far only a few sets of results have been published. However it is already clear that these analyses provide accurate measurements of gene expression in T cells. This technology offers the first opportunity to examine global and subtle changes in gene expression in response to specific stimuli.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
-
Review
MeSH terms
-
Animals
-
Cell Separation
-
Databases, Factual
-
Expressed Sequence Tags
-
Gene Expression Profiling*
-
Gene Expression Regulation / drug effects
-
Genome*
-
Hot Temperature
-
Humans
-
Jurkat Cells
-
Lymphocyte Activation / drug effects
-
Lymphocyte Activation / genetics*
-
Mice
-
Oligonucleotide Array Sequence Analysis*
-
Phorbol Esters / pharmacology
-
RNA, Messenger / analysis
-
RNA, Messenger / biosynthesis
-
RNA, Messenger / genetics
-
T-Lymphocytes / drug effects
-
T-Lymphocytes / immunology*
-
T-Lymphocytes / metabolism
Substances
-
Phorbol Esters
-
RNA, Messenger