Ampulla cardiomyopathy ('Takotusbo' cardiomyopathy)--reversible left ventricular dysfunction: with ST segment elevation

Jpn Circ J. 2000 Feb;64(2):156-9. doi: 10.1253/jcj.64.156.


The clinicopathologic findings of reversible ampulla-like ventriculogram of the left ventricle were studied in 8 elderly women and one middle-aged man. Their coronary arteriograms were normal, even in the 7 patients who had ST elevation on electrocardiogram. Coronary spasm was positive in only 2 of the 7 patients who received provocation tests. Biopsy specimens revealed focal myocyte injury. Normal coronary arteriograms during ST elevation and the presence of pathologic myocardial lesions were not consistent with a concept of stunned myocardium. The presence of myocardial lesions suggested that focal and disseminated myocardial damage had occurred.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiomyopathies / physiopathology*
  • Coronary Angiography
  • Electrocardiography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Ventricular Dysfunction, Left*