New polyethylene glycol electrolyte solution for the treatment of constipation and faecal impaction

Ital J Gastroenterol Hepatol. 1999 Nov;31 Suppl 3:S249-52.


Results from a controlled clinical trial indicate that low doses of polyethylene glycol solutions are more effective and have fewer side-effects than lactulose. Large doses of polyethylene glycol are effective in the treatment of faecal impaction. Resolution of faecal impaction was obtained in all patients, and in 25/30 patients with three administrations in a three-day period.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cathartics / therapeutic use*
  • Constipation / drug therapy*
  • Fecal Impaction / drug therapy*
  • Female
  • Humans
  • Lactulose / therapeutic use
  • Male
  • Middle Aged
  • Pilot Projects
  • Polyethylene Glycols / therapeutic use*
  • Single-Blind Method


  • Cathartics
  • Polyethylene Glycols
  • Lactulose