The prenatal pituitary gland--hidden and forgotten

Pediatr Neurol. 2000 Feb;22(2):155-6. doi: 10.1016/s0887-8994(99)00130-7.


The sella turcica and pituitary gland in a human fetus (18 weeks gestation) with unilateral oro-ocular cleft combined with unilateral cleft lip and palate are described histologically. In this fetus the sella turcica was not a normal sella but a caudally open funnel. The adenopituitary gland tissue was positioned ectopically within the funnel canal and in the pharyngeal submucosa.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abnormalities, Multiple / embryology
  • Choristoma
  • Embryonic and Fetal Development
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Maxillofacial Abnormalities / embryology*
  • Maxillofacial Abnormalities / etiology
  • Pharyngeal Diseases / embryology*
  • Pituitary Gland / abnormalities*
  • Pituitary Gland / embryology
  • Respiratory Mucosa / embryology
  • Sella Turcica / abnormalities*
  • Sella Turcica / embryology