Psychopharmacology in supportive care of cancer: a review for the clinician: II. Neuroleptics

Support Care Cancer. 2000 Mar;8(2):89-97. doi: 10.1007/s005200050021.


Neuroleptics are frequently used in patients with advanced cancer. Most relevant and practical aspects of their use in supportive cancer care are reviewed, to assist the clinical oncologist and palliative care specialist when prescribing these drugs. This article reviews pharmacological properties, indications, such as delirium, nausea and vomiting, pain, anxiety and other symptoms, adverse effects, and drug interactions of neuroleptics and compares the profiles of different compounds. Special emphasis is put on the role of neuroleptics in the management of delirium.

Publication types

  • Review

MeSH terms

  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / pharmacology
  • Antipsychotic Agents / therapeutic use*
  • Delirium / drug therapy*
  • Drug Interactions
  • Humans
  • Neoplasms / psychology*
  • Palliative Care*
  • Psychotropic Drugs / adverse effects
  • Psychotropic Drugs / pharmacology
  • Psychotropic Drugs / therapeutic use*


  • Antipsychotic Agents
  • Psychotropic Drugs