Two studies were conducted to examine the effects of job familiarity and impression management on response latencies and scale scores for measures of personality and situational judgment. In a laboratory study using university students and a field study using U.S. Border Patrol Agent applicants, impression management was generally associated with faster personality item responses when job familiarity was high and with slower responses when job familiarity was low. Both impression management and job familiarity were associated with personality item responses that were more likely to lead to a job offer. The field study revealed a similar pattern of results for situational judgment scale response latencies, although only impression management was associated with item responses that were more likely to lead to a job offer. The implications for using response latencies to detect impression management on self-report measures are discussed.