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Review
, 6 (4), 389-95

Mechanisms of Angiogenesis and Arteriogenesis

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Review

Mechanisms of Angiogenesis and Arteriogenesis

P Carmeliet. Nat Med.

Abstract

Endothelial and smooth muscle cells interact with each other to form new blood vessels. In this review, the cellular and molecular mechanisms underlying the formation of endothelium-lined channels (angiogenesis) and their maturation via recruitment of smooth muscle cells (arteriogenesis) during physiological and pathological conditions are summarized, alongside with possible therapeutic applications.

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