[Cerebral venous thrombosis after lumbar puncture and intravenous steroids in two patients with multiple sclerosis]

Rev Neurol (Paris). 2000 Feb;156(2):155-9.
[Article in French]


Two patients affected with a multiple sclerosis developed cerebral venous thrombosis after lumbar puncture and treatment with intravenous methylprednisolone. In one case, the course was favorable. The second patient died in spite of intracerebral thrombolysis. The autopsy confirmed the diagnosis of cerebral venous thrombosis and multiple sclerosis. We discuss the relationship between lumbar puncture, steroid treatment and cerebral venous thrombosis.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adrenal Cortex Hormones / adverse effects*
  • Adult
  • Fatal Outcome
  • Female
  • Humans
  • Intracranial Thrombosis / diagnosis
  • Intracranial Thrombosis / drug therapy
  • Intracranial Thrombosis / etiology*
  • Male
  • Middle Aged
  • Multiple Sclerosis / diagnosis*
  • Multiple Sclerosis / drug therapy*
  • Spinal Puncture / adverse effects*
  • Thrombolytic Therapy
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / drug therapy
  • Venous Thrombosis / etiology*


  • Adrenal Cortex Hormones