Diagnosis and management of spinal epidural space extravasation complicating percutaneous central venous line placement in a premature infant: case report and review of literature

Conn Med. 2000 Feb;64(2):79-82.


Percutaneous central venous lines are commonly used to establish long-term venous access in the care of premature infants. Misplacement of these catheters can occur and may lead to significant morbidity and mortality. Here we report a very-low-birth-weight premature infant whose percutaneous central venous line was inadvertently placed into the spinal epidural space. The anatomical basis of this complication as well as a comprehensive review of literature are provided.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Catheterization, Central Venous / adverse effects*
  • Catheterization, Central Venous / instrumentation
  • Epidural Space*
  • Extravasation of Diagnostic and Therapeutic Materials / diagnosis*
  • Extravasation of Diagnostic and Therapeutic Materials / therapy
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Premature, Diseases / diagnosis*
  • Infant, Premature, Diseases / therapy
  • Infant, Very Low Birth Weight*
  • Parenteral Nutrition / adverse effects
  • Parenteral Nutrition / instrumentation
  • Saphenous Vein