Long-term persistence of a discotheque-associated invasive Neisseria meningitidis group C strain as proven by pulsed-field gel electrophoresis and porA gene sequencing

K Riesbeck; P Orvelid-Mölling; H Fredlund; P Olcén

doi:10.1128/JCM.38.4.1638-1640.2000

Long-term persistence of a discotheque-associated invasive Neisseria meningitidis group C strain as proven by pulsed-field gel electrophoresis and porA gene sequencing

J Clin Microbiol. 2000 Apr;38(4):1638-40. doi: 10.1128/JCM.38.4.1638-1640.2000.

Authors

K Riesbeck¹, P Orvelid-Mölling, H Fredlund, P Olcén

Affiliation

¹ Department of Medical Microbiology, Malmö University Hospital, Lund University, S-205 02 Malmö, Sweden. kristian.riesbeck@mikrobiol.mas.lu.se

Abstract

A cluster of a Neisseria meningitidis serogroup C strain causing invasive disease was investigated. Five out of seven cases were associated with a particular discotheque. The strains were indistinguishable, as revealed by pulsed-field gel electrophoresis and sequencing of variable regions of the porA gene, but caused strikingly different clinical presentations during 5 months.

MeSH terms

Adolescent
Adult
Child
Child, Preschool
Dancing*
Disease Outbreaks*
Electrophoresis, Gel, Pulsed-Field*
Female
Humans
Infant
Male
Meningococcal Infections / epidemiology*
Meningococcal Infections / microbiology
Middle Aged
Neisseria meningitidis / classification
Neisseria meningitidis / genetics
Neisseria meningitidis / pathogenicity*
Porins / genetics*
Sweden / epidemiology

Substances

Porins
porin protein, Neisseria