ST Segment and T Wave Alternans in a Patient With Brugada Syndrome

Pacing Clin Electrophysiol. 2000 Mar;23(3):413-5. doi: 10.1111/j.1540-8159.2000.tb06773.x.

Abstract

We describe a patient with Brugada syndrome in whom J point and ST-segment elevation in leads V1 and V2 were augmented by atrial pacing and intravenous administration of propranolol or cibenzoline. Significant T wave alternans with a 2:1 appearance of terminal negative T wave was observed in the absence and presence of atrial pacing after the administration of cibenzoline. The cellular mechanism responsible for T wave alternans, beat-to-beat appearance of terminal negative T wave and augmented J point and ST-segment elevation is discussed.

Publication types

  • Case Reports

MeSH terms

  • Bundle-Branch Block / physiopathology*
  • Electrocardiography*
  • Humans
  • Male
  • Middle Aged
  • Syndrome
  • Ventricular Fibrillation / physiopathology*