The post-prandial state and cardiovascular disease: relevance to diabetes mellitus

Diabetes Metab Res Rev. Mar-Apr 2000;16(2):125-32. doi: 10.1002/(sici)1520-7560(200003/04)16:2<125::aid-dmrr90>;2-4.


There is increasing evidence that the post-prandial state is an important contributing factor to the development of atherosclerosis. In non-diabetic subjects the atherosclerotic risk factors comprised in the categories of lipids, coagulation system and endothelial function may be adversely modified in the post-prandial phase. The generation of an oxidative stress may be the common pathway through which eating may induce these alterations. In diabetic patients these phenomena may be amplified by post-prandial hyperglycemia.

Publication types

  • Review

MeSH terms

  • Arteriosclerosis / epidemiology
  • Arteriosclerosis / physiopathology*
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / physiopathology*
  • Diabetes Mellitus / physiopathology*
  • Diabetic Angiopathies / physiopathology*
  • Humans
  • Hyperglycemia / physiopathology
  • Postprandial Period*