Malignant spinal neurofibrosarcoma

Spine (Phila Pa 1976). 2000 Mar 15;25(6):752-5. doi: 10.1097/00007632-200003150-00019.


Study design: A report of a case of metastatic spinal neurofibrosarcoma.

Objective: To document metastatic neurofibrosarcoma as a cause of spinal cord compression and to review the literature.

Summary of background data: Three previously reported cases of metastatic neurofibrosarcoma of the spine were reviewed.

Methods: The patient's clinical record and radiologic investigations as well as the result of a search of the English literature are reported. Magnetic resonance images, computed tomographic scans, and histology photomicrographs are displayed.

Results: Paraparesis developed in this patient, due to a posterior extradural thoracic spinal cord compression by a neurofibrosarcoma believed to be metastatic from a neurofibrosarcoma of the femoral nerve.

Conclusions: Malignant spinal metastasis remains a rare complication of neurofibromatosis, with a very poor prognosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Fatal Outcome
  • Humans
  • Laminectomy
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurofibroma / pathology
  • Neurofibrosarcoma / complications
  • Neurofibrosarcoma / diagnosis
  • Neurofibrosarcoma / secondary*
  • Neurofibrosarcoma / surgery
  • Soft Tissue Neoplasms / pathology
  • Spinal Cord Compression / etiology
  • Spinal Cord Compression / surgery
  • Spinal Cord Neoplasms / complications
  • Spinal Cord Neoplasms / diagnosis
  • Spinal Cord Neoplasms / secondary*
  • Spinal Cord Neoplasms / surgery
  • Tomography, X-Ray Computed