Working memory and executive function: evidence from neuroimaging

Curr Opin Neurobiol. 2000 Apr;10(2):195-9. doi: 10.1016/s0959-4388(00)00074-x.

Abstract

Traditional theories of working memory and executive function, when mapped in straightforward ways into the neural domain, yield predictions that are only partly supported by the recent neuroimaging studies. Neuroimaging studies suggest that some constituent functions, such as maintaining information in active form and manipulating it, are not discretely localized in prefrontal regions. Some hypothesized executive processes, such as goal management, have effects in several cortical regions, including posterior regions. Such results suggest a more dynamic and distributed view of the cortical organization of working memory and executive functions.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Brain Mapping*
  • Cerebral Cortex / anatomy & histology
  • Cerebral Cortex / diagnostic imaging
  • Cerebral Cortex / physiology
  • Cognition / physiology
  • Diagnostic Imaging / methods*
  • Humans
  • Image Enhancement / methods
  • Magnetic Resonance Imaging
  • Memory, Short-Term / physiology*
  • Tomography, Emission-Computed
  • Volition / physiology*