Bacteroides fragilis enterotoxin gene sequences in patients with inflammatory bowel disease

Emerg Infect Dis. Mar-Apr 2000;6(2):171-4. doi: 10.3201/eid0602.000210.

Abstract

We identified enterotoxigenic Bacteroides fragilis in stool specimens of patients with inflammatory bowel disease and other gastrointestinal disorders. The organism was detected in 11 (13.2%) of 83 patients with inflammatory bowel disease. Of 57 patients with active disease, 19.3% were toxin positive; none of those with inactive disease had specimens positive for enterotoxigenic Bacteroides fragilis gene sequences.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Bacteroides Infections / etiology
  • Bacteroides Infections / microbiology
  • Bacteroides fragilis / genetics*
  • Bacteroides fragilis / pathogenicity*
  • Case-Control Studies
  • Child
  • DNA, Bacterial / genetics
  • DNA, Bacterial / isolation & purification
  • Enterotoxins / genetics*
  • Feces / microbiology
  • Female
  • Genes, Bacterial*
  • Humans
  • Inflammatory Bowel Diseases / etiology
  • Inflammatory Bowel Diseases / microbiology*
  • Male
  • Metalloendopeptidases / genetics*
  • Middle Aged

Substances

  • DNA, Bacterial
  • Enterotoxins
  • Metalloendopeptidases
  • fragilysin