Treatment of Charles Bonnet syndrome with valproate

Int Clin Psychopharmacol. 2000 Mar;15(2):117-9. doi: 10.1097/00004850-200015020-00009.


Charles Bonnet syndrome (CBS), as described in the psychiatric literature, refers to pseudohallucinations in elderly people who frequently suffer from reduced visual acuity. There is no established treatment for CBS. We report two cases involving elderly women with CBS who were successfully treated with valproate. The present results suggest that valproate can be useful for CBS in some patients.

Publication types

  • Case Reports

MeSH terms

  • Age Factors
  • Aged
  • Antimanic Agents / pharmacology
  • Antimanic Agents / therapeutic use*
  • Female
  • Hallucinations / drug therapy*
  • Hallucinations / psychology
  • Humans
  • Syndrome
  • Treatment Outcome
  • Valproic Acid / pharmacology
  • Valproic Acid / therapeutic use*
  • Visual Perception


  • Antimanic Agents
  • Valproic Acid